Focuses on methods of inquiry as a basis for the expansion of nursing knowledge and application of research in advanced clinical practice. Selection of research methods to identify client-focused clinical nursing problems and appropriate interventions in advanced practice are addressed within an ethical context. The course provides a basis for evaluation of published evidence and research, supports application of formalized quantitative and qualitative methods to practice, and prepares the graduate to practice evidence-based practice and conduct quantitative and qualitative research studies. Epidemiological trends will be addressed as one of the methods utilized for identification of client related problems. Analysis of research studies and the identification of a specific research problem in nursing, a specific research design, and the development of a research proposal are expected outcomes of this course.